HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1328674
rs1328674 		1.000 0.120 13 46867572 intron variant T/C;G snv
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1923885
rs1923885 		1.000 0.040 13 46848951 intron variant T/C snv 0.43
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs643627
rs643627 		1.000 0.040 13 46854476 intron variant T/C snv 0.27
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		Mental Disorders 0.010 1.000 1 2018 2018
dbSNP: rs6561333
rs6561333 		1.000 0.080 13 46846177 intron variant T/C snv 0.60
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		Chemically-Induced Disorders; Mental Disorders 0.010 1.000 1 2013 2013
dbSNP: rs9534511
rs9534511 		1.000 0.040 13 46894445 intron variant T/C snv 0.54
CUI: C0424296
Disease: Social disinhibition
Social disinhibition 		Mental Disorders 0.010 1.000 1 2014 2014
dbSNP: rs7984966
rs7984966 		13 46855311 intron variant T/A;C snv
CUI: C0424101
Disease: Inattention
Inattention 		0.010 1.000 1 2016 2016
dbSNP: rs7322347
rs7322347 		1.000 0.040 13 46835968 intron variant T/A snv 0.49
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 2019 2019
dbSNP: rs12584920
rs12584920 		1.000 0.040 13 46890902 intron variant G/C;T snv
CUI: C3178789
Disease: Widespread Chronic Pain
Widespread Chronic Pain 		Pathological Conditions, Signs and Symptoms 0.010 1.000 1 2011 2011
dbSNP: rs1805055
rs1805055 		0.882 0.120 13 46895833 missense variant G/C;T snv 2.0E-05; 1.8E-02
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.010 1.000 1 1997 1997
dbSNP: rs1805055
rs1805055 		0.882 0.120 13 46895833 missense variant G/C;T snv 2.0E-05; 1.8E-02
CUI: C4694057
Disease: Taq1A POLYMORPHISM
Taq1A POLYMORPHISM 		0.010 1.000 1 2007 2007
dbSNP: rs1805055
rs1805055 		0.882 0.120 13 46895833 missense variant G/C;T snv 2.0E-05; 1.8E-02
CUI: C0027849
Disease: Neuroleptic Malignant Syndrome
Neuroleptic Malignant Syndrome 		Nervous System Diseases; Chemically-Induced Disorders 0.010 1.000 1 1998 1998
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.100 0.810 42 1996 2019
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		Mental Disorders 0.100 0.933 15 2000 2019
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.100 0.917 12 2003 2019
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		Mental Disorders 0.100 1.000 11 2000 2019
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0438696
Disease: Suicidal
Suicidal 		Behavior and Behavior Mechanisms 0.080 1.000 8 2000 2013
dbSNP: rs6314
rs6314 		0.677 0.360 13 46834899 missense variant G/A snv 7.9E-02 9.5E-02
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.080 1.000 8 1998 2017
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders 		Mental Disorders 0.070 0.857 7 2007 2017
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		Mental Disorders 0.060 1.000 6 2001 2016
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0349204
Disease: Nonorganic psychosis
Nonorganic psychosis 		Mental Disorders 0.060 1.000 6 2007 2017
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0021125
Disease: Impulsive Behavior
Impulsive Behavior 		Behavior and Behavior Mechanisms 0.060 1.000 6 2002 2018
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		Mental Disorders 0.050 1.000 5 2006 2014
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		Mental Disorders 0.050 1.000 5 2003 2014
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0016053
Disease: Fibromyalgia
Fibromyalgia 		Musculoskeletal Diseases; Nervous System Diseases 0.050 0.600 5 1999 2012
dbSNP: rs6313
rs6313 		0.562 0.640 13 46895805 synonymous variant G/A snv 0.41 0.40
CUI: C0520679
Disease: Sleep Apnea, Obstructive
Sleep Apnea, Obstructive 		Respiratory Tract Diseases; Nervous System Diseases 0.050 0.800 5 2011 2015